首页> 外文期刊>The journal of clinical endocrinology and metabolism >Pituitary Tumor Suppression by Combination of Cabergoline and Chloroquine
【24h】

Pituitary Tumor Suppression by Combination of Cabergoline and Chloroquine

机译:卡麦角林与氯喹联用抑制垂体肿瘤

获取原文
       

摘要

AbstractContextThe dopamine agonist cabergoline (CAB) has been used widely in the treatment of prolactinomas and other types of pituitary adenomas, but its clinical use is hampered by intolerance in some patients with prolactinoma and lack of effectiveness in other pituitary tumor types. Chloroquine (CQ) is an old drug widely used to treat malaria. Recent studies, including our own, have revealed that CAB and CQ are involved in induction of autophagy and activation of autophagic cell death.
机译:摘要背景多巴胺激动剂卡麦角林(CAB)已被广泛用于治疗催乳素瘤和其他类型的垂体腺瘤,但由于某些催乳素瘤患者不耐受且在其他垂体瘤类型中缺乏疗效,因此其临床应用受到阻碍。氯喹(CQ)是一种广泛用于治疗疟疾的老药。最近的研究,包括我们自己的研究,已经表明CAB和CQ参与自噬的诱导和自噬细胞死亡的激活。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号