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Adrenal Myelolipoma: An Unusual Cause of Bilateral Highly 18F-FDG-Avid Adrenal Masses

机译:肾上腺髓样脂肪瘤:双侧高度18F-FDG-Avid肾上腺肿块的异常原因

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A77-yr-old man presented with rapidly progressive cer-ebellarsyndrome,extrapyramidalsigns,andcognitiveimpairment.Pastmedicalhistoryreportedaprostatecancertreated by external radiotherapy and an essential thrombo-cytemia with sideroblastic anemia. Brain computed tomog-raphy (CT) scan was normal. The combination of positiveantineutrophil antibodies and brain 18F-fluorodeoxyglu-cose (18F-FDG) positron emission tomography (PET) up-take pattern was suggestive of paraneoplastic neurologicalsyndrome. Whole-body PET imaging revealed bilateral hy-permetabolic adrenal masses (right and left adrenal maxi-mumstandardizeduptakevalue?11.4and8.0).AbdominalCTscanshowedbilateralheterogeneousadrenalmassescon-taining soft tissue and adipose components (Fig. 1). Com-plete endocrinological workup (24-h urinary free cortisol,low-dose dexamethasone suppression test, plasma aldoste-ronelevel,dehydroepiandrosteronesulfate,andurinaryandplasmamethoxyamines)wasnormal.ACTscan-guidedad-renalpuncturewasperformedtoruleoutmalignancy.Path-ological analyses were concordant with the diagnosis ofmyelolipoma.
机译:一名77岁的男性,表现为快速进行性脑脊髓综合征,锥体外系征和认知障碍。过去的医学史报道前列腺癌接受了外部放疗和原发性血栓性细胞增多症并伴有铁粒幼细胞性贫血。脑计算机断层扫描(CT)扫描正常。阳性抗中性粒细胞抗体和脑18F-氟脱氧-葡萄糖(18F-FDG)正电子发射断层扫描(PET)摄取模式的组合提示副肿瘤性神经系统综合症。全身PET显像显示双侧高代谢性肾上腺肿块(右,左肾上腺最大标准化摄取值分别为11.4和8.0)。腹部CT扫描显示双侧异质肾上腺肿块包含软组织和脂肪成分(图1)。完整的内分泌检查正常(24小时尿游离皮质醇,低剂量地塞米松抑制试验,血浆醛固酮水平,脱氢表雄酮硫酸盐,尿及血浆和血浆甲氧基胺),正常。

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