Deletions of the Androgen-Metabolizing UGT2B Genes Have an Effect on Circulating Steroid Levels and Biochemical Recurrence after Radical Prostatectomy in Localized Prostate Cancer

Geneviève Nadeau; Judith Bellemare; étienne Audet-Walsh; Christine Flageole; Shu-Pin Huang; Bo-Ying Bao; Pierre Douville; Patrick Caron; Yves Fradet; Louis Lacombe; Chantal Guillemette; Eric Lévesque

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Deletions of the Androgen-Metabolizing UGT2B Genes Have an Effect on Circulating Steroid Levels and Biochemical Recurrence after Radical Prostatectomy in Localized Prostate Cancer

机译：雄激素代谢性UGT2B基因的缺失对局限性前列腺癌根治性前列腺切除术后循环类固醇水平和生化复发的影响

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Context:The prognostic relevance of inherited variations in hormone-related genes in the context of prostate cancer (PCa) progression has not been well studied. Of these, UDP-glucuronosyltransferase ( UGT ) gene products lead to inactivation of steroids.

机译：背景：在前列腺癌（PCa）进展的背景下，激素相关基因遗传变异的预后相关性尚未得到很好的研究。其中，UDP-葡萄糖醛酸转移酶（UGT）基因产物导致类固醇失活。

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《The journal of clinical endocrinology and metabolism》 |2011年第9期|共8页
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Geneviève Nadeau; Judith Bellemare; étienne Audet-Walsh; Christine Flageole; Shu-Pin Huang; Bo-Ying Bao; Pierre Douville; Patrick Caron; Yves Fradet; Louis Lacombe; Chantal Guillemette; Eric Lévesque;
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1. Deletions of the Androgen-Metabolizing UGT2B Genes Have an Effect on Circulating Steroid Levels and Biochemical Recurrence after Radical Prostatectomy in Localized Prostate Cancer [J] . Geneviève Nadeau, Judith Bellemare, étienne Audet-Walsh, The journal of clinical endocrinology and metabolism . 2011,第9期

机译：雄激素代谢性UGT2B基因的缺失对局限性前列腺癌根治性前列腺切除术后循环类固醇水平和生化复发的影响
2. The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy [J] . Sung Han Kim, Weon Seo Park, Sang Jin Lee, BioMed research international . 2015,第41期

机译：相对于GAPDH水平的循环前列腺干细胞抗原mRNA的量化水平是用于在自由基前列腺切除术后预测前列腺癌患者的生物化学复发的临床显着的指标
3. The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy [J] . Sung HanKim, Weon SeoPark, Sang JinLee, BioMed research international . 2015,第1期

机译：相对于GAPDH水平的循环前列腺干细胞抗原mRNA定量水平是预测前列腺癌根治术后前列腺癌患者生化复发的临床重要指标
4. Pretreatment Serum Testosterone Level Can Predict Pathological Stage in Localized Prostate Cancer Patients Treated with Radical Prostatectomy [C] . T. Imamoto, H. Suzuki, S. Fukasawa, International Congress of Andrology . 2005

机译：预处理血清睾酮水平可以预测局部前列腺癌患者的病理阶段，其患有自由基前列腺切除术治疗
5. Psychological reactions to biochemical recurrence after radical prostatectomy in men with localized prostate cancer [D] . Esfarayeni, Maryam. 2006

机译：前列腺癌患者根治性前列腺切除术后对生化复发的心理反应
6. The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy [O] . Sung Han Kim, Weon Seo Park, Sang Jin Lee, -1

机译：相对于GAPDH水平的定量循环前列腺干细胞抗原mRNA水平是预测前列腺癌根治术后前列腺癌患者生化复发的重要临床指标
7. Deletions of the Androgen-MetabolizingUGT2BGenes Have an Effect on Circulating Steroid Levels and Biochemical Recurrence after Radical Prostatectomy in Localized Prostate Cancer [O] . Geneviève Nadeau, Judith Bellemare, Étienne Audet-Walsh, 2011

机译：雄激素 - 代谢溶剂的缺失对局部前列腺癌自由基前列腺切除术后循环类固醇水平和生化复发的作用

Deletions of the Androgen-Metabolizing UGT2B Genes Have an Effect on Circulating Steroid Levels and Biochemical Recurrence after Radical Prostatectomy in Localized Prostate Cancer

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