Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice

Panudda Srichomkwun; Jo#227; o Anselmo; Xiao-Hui Liao; G Sebastian H#246; nes; Lars C Moeller; Manuela Alonso-Sampedro; Roy E Weiss; Alexandra M Dumitrescu; Samuel Refetoff

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Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice

机译：胎儿暴露于高水平的孕妇甲状腺激素会导致成年人和小鼠对甲状腺激素的中枢抵抗

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AbstractContextFetuses exposed to the high thyroid hormone (TH) levels of mothers with resistance to thyroid hormone beta (RTH-β), due to mutations in the THRB gene, have low birth weight and suppressed TSH.

机译：摘要背景由于THRB基因突变而暴露于对甲状腺激素β（RTH-β）有抵抗力的母亲的甲状腺激素（TH）水平高的胎儿，出生体重低且TSH受到抑制。

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《The journal of clinical endocrinology and metabolism》 |2017年第9期|共7页
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Panudda Srichomkwun; Jo#227; o Anselmo; Xiao-Hui Liao; G Sebastian H#246; nes; Lars C Moeller; Manuela Alonso-Sampedro; Roy E Weiss; Alexandra M Dumitrescu; Samuel Refetoff;
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1. Behavioral deficits associated with fetal alcohol exposure are reversed by prenatal thyroid hormone treatment: a role for maternal thyroid hormone deficiency in FAE [J] . J S Wilcoxon, A G Kuo, J F Disterhoft, Molecular Psychiatry . 2005,第10期

机译：产前甲状腺激素治疗可逆转与胎儿酒精暴露相关的行为缺陷：FAE中孕妇甲状腺激素缺乏的作用
2. Fetal and neonatal iron deficiency exacerbates mild thyroid hormone insufficiency effects on male thyroid hormone levels and brain thyroid hormone-responsive gene expression [J] . BastianT.W., ProhaskaJ.R., GeorgieffM.K., Endocrinology . 2014,第3期

机译：胎儿和新生儿缺铁会加重轻度甲状腺激素不足，对男性甲状腺激素水平和脑甲状腺激素反应性基因表达的影响
3. Developmental Changes in Rat Brain 5|[prime]|-Deiodinase and Thyroid Hormones during the Fetal Period: The Effects of Fetal Hypothyroidism and Maternal Thyroid Hormones [J] . Carmen Ruiz De O?a, Maria Jesus Obregón, Francisco Escobar Del Rey, Pediatric Research . 1988,第5期

机译：胎儿期大鼠脑5 | [prime] |-脱碘酶和甲状腺激素的发育变化：胎儿甲状腺功能减退症和母体甲状腺激素的影响
4. Associations between Organophosphate Flame Retardant Exposure during Pregnancy and Reproductive and Thyroid Hormone Levels: A Preliminary Analysis [C] . Deborah Watkins, Zaira Rosario, Jose Cordero, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：孕期有机磷阻燃剂暴露与生殖和甲状腺激素水平之间的关联：初步分析
5. Effects of thyroid hormones, thyroid hormone disruptors, and treated wastewater on bullfrog tadpole chemosensory function and behaviour. [D] . Heerema, Jody L. 2017

机译：甲状腺激素，甲状腺激素干扰物和处理过的废水对牛蛙t化学感应功能和行为的影响。
6. Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice [O] . Panudda Srichomkwun, João Anselmo, Xiao-Hui Liao, -1

机译：胎儿暴露于高水平的孕妇甲状腺激素会导致成年人和小鼠对甲状腺激素的中枢抵抗
7. Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice [O] . Panudda Srichomkwun, João Anselmo, Xiao-Hui Liao, 2017

机译：胎儿暴露于高母体甲状腺激素水平导致成人人和小鼠中的甲状腺激素导致甲状腺激素

Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice

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