Placenta Mesenchymal Dysplasia, After Successful Management Of Infertility

摘要

A 23 year old Qatari female was followed for infertility for two years in the IVF unit in woman hospital in Doha, Hamad Medical Corporation, Qatar. After two years of medical follow up and treatment, IVF was tried and the patient got pregnant. Follow-up during pregnancy continued and the pregnancy ended by full term live born boy. Histological examination of a placentomegally showed placental mesenchymal dysplasia. Herein, we represent this interesting case of infertility managed by IVF, which was associated with placental mesenchymal dysplasia, with review of literatures. Case Study A 23 year old primigravida Qatari, who had a history of infertility for two years. Full medical and gynecological follow up of the patient showed that the patient had a high prolactin level. MRI was performed and showed slight enlargement of the right lobe of the pituitary. Her thyroid function test was normal and she was slightly anemic. IVF was successfully tried with this patient and resulted in pregnancy. An Array comparative genomic hybridization (aCGH) done and the result was a normal microarray, male "arr (1-22) x2, (XY) x1". The obstetric ultrasound showed single cephalic fetus of 37 gestational weeks weighing 2904 grams with normal heart beat and fetal movements. The patient delivered a live male baby. Histopathology of the placenta showed placentomegally of 935 grams with obvious vesicles on the surface. Histology revealed placental mesenchymal dysplasia.