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Nasal Hemangiopericytoma –A Pathological Illusion

机译:鼻血管内皮细胞瘤–一种病理错觉

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Objective: We report a case of rare nasal mass whose histopathological diagnosis was lobular capillary hemangioma but immunohistochemistry reported it to be hemangiopericytoma.Case report: Lobular capillary hemangioma and hemangiopericytoma are very rare vascular tumours arising from the nasal cavity. Here we report a case of rare nasal mass, which presented with nasal obstruction and epistaxis. Frozen section biopsy reported benign vascular tumour. Final biopsy report of excised mass was sent to different pathologists at different places. Both of them confirmed to the diagnosis of lobular capillary hemangioma. Due to atypical clinical picture which was not correlating with the histopathological diagnosis, tissue was sent for immunohistochemistry, which altered the final diagnosis to hemangiopericytoma.Conclusions: Every nasal mass should be looked with suspicion especially in older age group and patient should be kept under close observation. The facility of immunohiostochemistry should be utilized in cases where there is lack of clinicopathological correlation. Introduction Among common benign nasal masses lobular capillary hemangioma and hemangiopericytoma are very rare vascular tumours arising from the nasal cavity. The clinical picture, course and treatment of both these tumours is entirely different. Histopathological picture of both these tumours is sometimes very confusing which creates dilemma for the treating surgeon to suggest the patient about prognosis of the disease and final outcome of the treatment. Here comes the role of immunohistochemistry, which can differentiate between different tumours by using different stains. Case report A 43 year old male patient presented to our OPD with chief complaints of epistaxis, nasal obstruction and headache from last two months. Epistaxis was episodic, relieved spontaneously and never required hospitalization. There was no history of hypertension, trauma or any other major systemic illness. On examination of nose there was no external deformity. On anterior rhinoscopy left side of nasal cavity was filled with a mass (Fig.1) which was dirty white in colour, non tender, friable, firm to soft in consistency and there was no bleeding in probing the mass.
机译:目的:我们报道一例罕见的鼻腔肿物,其组织病理学诊断为小叶性毛细血管瘤,但免疫组织化学报告为小血管性毛细血管瘤。病例报告:小叶性毛细血管瘤和血管性皮细胞瘤是由鼻腔引起的非常罕见的血管肿瘤。在这里,我们报告一例罕见的鼻腔肿块,表现为鼻塞和鼻epi。冷冻切片活检报告良性血管肿瘤。切除的肿块的最终活检报告已发送给不同地方的不同病理学家。他们都证实了小叶性毛细血管瘤的诊断。由于不典型的临床表现与组织病理学诊断无关,因此组织被送去进行免疫组织化学检查,从而改变了对血管内皮细胞瘤的最终诊断。结论:尤其是在年龄较大的人群中,应仔细检查每个鼻腔肿物,并保持患者密闭观察。在缺乏临床病理相关性的情况下,应使用免疫组织化学的设施。引言在常见的良性鼻腔肿块中,小叶毛细管血管瘤和血管周细胞瘤是由鼻腔引起的非常罕见的血管肿瘤。这两种肿瘤的临床图片,病程和治疗方法完全不同。这两种肿瘤的组织病理学图像有时会非常令人困惑,这给治疗的外科医生带来了两难境地,即向患者建议疾病的预后和治疗的最终结果。免疫组织化学的作用来了,它可以通过使用不同的染色剂来区分不同的肿瘤。病例报告一名来自我们的OPD的43岁男性患者自最近两个月以来主要抱怨鼻epi,鼻塞和头痛。鼻出血是偶发性的,自发缓解,不需要住院。没有高血压,外伤或任何其他重大全身性疾病的病史。鼻子检查没有外部畸形。在鼻腔镜检查前,鼻腔左侧充满肿块(图1),其颜色为白色,不嫩,易碎,结实至软,并且在探查肿块时无出血。

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