Background and Objectives: More insight is needed into the link between loneliness and schizoid personality disorder in order to construct more adequate diagnostic tools and therapeutic programs. Methods: A computer-based search of literature (Medline and PsycInfo) between 1970 and 2009. Results: A combination of intrapsychic, psychosocial, cultural, ethnic, religious, and/or neurobiological factors determine loneliness and associated schizoid etiology. Furthermore, a complex interaction between these influences is prevalent in schizoid etiology. Conclusion: Loneliness appears to be a crucial factor in the etiology of schizoid personality disorder.
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