Comment on the combination of mifepristone and misoprostol for the termination of second-trimester pregnancy

摘要

We are happy to see Li et al's [1] report in the 2011 issue of the Taiwanese Journal of Obstetrics and Gynecology, which provided a good suggestion for our clinical practice. Dr. Li et al [1] suggested that the combination of mifepristone and misoprostol was safe and effective for first-trimester pregnancy termination. The above-mentioned suggestion is worthy of being announced again, since much evidence supported that concurrent mifepristone and misoprostol is more effective than prostaglandin derivatives alone for second- or third-trimester abortion. In fact, two other published articles in the same year (2011) in the Taiwanese Journal of Obstetrics and Gynecology also highlighted the benefits of the combined therapy compared with each alone [2], [3].