In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase

Barreto Junior Cleber Bomfim; Gomes Anne Caroline Candido; Instituto Federal de Educa??o Ciência e Tecnologia do Rio de Janeiro Rio de Janeiro Brasil; Kuster Ricardo Machado; Lamas Marcelo Einicker; Sakuragui Cassia M?nica; Sampaio Luzia da Silva; Silva Paulo André da; Simas Naomi Kato; Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil

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In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase

机译：鬼臼叶总皂苷对猪肾脏Na +，K + -ATPase的体外作用

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The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.

机译：本研究旨在研究从鬼臼中分离得到的异沙糖苷对猪肾脏Na +，K + -ATPase的体外作用。 Na +，K + -ATPase活性是通过比色法测量由ATP水解产生的无机磷酸盐（Pi）来确定的。在最高浓度和较低浓度下，异黄酮甙均显着降低了肾脏的Na +，K + -ATPase活性。我们的工作表明异沙糖苷是治疗高血压的有前途的化合物。

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《Quimica nova 》 |2014年第10期| 共页
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Barreto Junior Cleber Bomfim; Gomes Anne Caroline Candido; Instituto Federal de Educa??o Ciência e Tecnologia do Rio de Janeiro Rio de Janeiro Brasil; Kuster Ricardo Machado; Lamas Marcelo Einicker; Sakuragui Cassia M?nica; Sampaio Luzia da Silva; Silva Paulo André da; Simas Naomi Kato; Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil;
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1. In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase [J] . Anne Caroline Candido Gomes, Cassia M?nica Sakuragui, Cleber Bomfim Barreto Junior, Química Nova . 2014 ,第10期

机译：鬼臼叶总皂苷对猪肾脏Na +，K + -ATPase的体外作用
2. Comparison of Digitalis Sensitivities of Na+/K+-ATPases from Human and Pig Kidneys [J] . Marjorie E. Gable, Linda Ellis, Olga V. Fedorova, ACS Omega . 2017 ,第7期

机译：Na + / sup> / k + -Atpase的洋地黄敏感性的比较人和猪肾脏
3. Conformational states of the pig kidney Na+/K+-ATPase differently affect bufadienolides and cardenolides: A directed structure-activity and structure-kinetics study [J] . Azalim Pedro, do Monte Fernando M., Rendeiro Mariana Manzano, Biochemical Pharmacology . 2020 ,第1期

机译：猪肾Na + / K + -ATPase的构象状态不同地影响Bufdienolides和心肺病：一种定向的结构 - 活性和结构 - 动力学研究
4. Performance of Dye Sensitized Solar Cells (DSSC) using Syngonium Podophyllum Schott as Natural Dye and Counter Electrode [C] . Lingga Ghufira Oktariza, Brian Yuliarto, Suyatman International Conference on the Science and Engineering of Materials . 2018

机译：使用合成阴道孢子肌肌肌肌染料敏化太阳能电池（DSSC）作为天然染料和对电极的性能
5. Temporal and steric analysis of ionic permeation and binding in Na+,K+-ATPase via molecular dynamic simulations. [D] . Fonseca, James E. 2008

机译：通过分子动力学模拟对Na +，K + -ATPase中离子渗透和结合的时空分析。
6. Comparison of Digitalis Sensitivities of Na+/K+-ATPases from Human and Pig Kidneys [O] . MarjorieE. Gable, Linda Ellis, Olga V. Fedorova, 2017

机译：人和猪肾脏中Na + / K + -ATPase的洋地黄敏感性比较
7. In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase [O] . Anne Caroline Candido Gomes, Luzia da Silva Sampaio, Paulo André da Silva, 2014

机译：从syngonium podophyllum中分离的异黄芩苷对猪肾Na +，K + -aTpase的体外作用

In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase

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