Two Cases of Recurrent Episodes of Angio Edema Without Urticaria or Pruritus

摘要

A 45 years old man reports recurrent episodes of marked lip and hand swelling; without urticaria or puritus occurring during surgical procedure for lymph nodes biopsy. He was diagnosed with lymphoma six months ago. He has had three episodes of severe, campy abdominal pain and bloating lasting up to 24–36 hours on the past year. No family history of Angioedema. Work up showed: CBC, chemistry and IgE were normal. C4 was 35 mg/dL (normal 50–100 mg/dl) C1 esterase inhibitor (C1 -INH) level: 18 mg/dL (normal 18–50 mg/dl), low C1 -INH function (less than 50% of normal) and low C1 q (less than 30% of normal)