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Racial/Ethnic Patterns in Prostate Cancer Outcomes in an Active Surveillance Cohort

机译:积极监测队列中前列腺癌患者的种族/种族模式

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Introduction. Concern regarding overtreatment of prostate cancer (CaP) is leading to increased attention on active surveillance (AS). This study examined CaP survivors on AS and compared secondary treatment patterns and overall survival by race/ethnicity.Methods. The study population consisted of CaP patients self-classified as black or white followed on AS in the Center for Prostate Disease Research (CPDR) multicenter national database between 1989 and 2008. Secondary treatment included radical prostatectomy (RP), external beam radiation therapy or brachytherapy (EBRT-Br), and hormone therapy (HT). Secondary treatment patterns and overall survival were compared by race/ethnicity.Results. Among 886 eligible patients, 21% were black. Despite racial differences in risk characteristics and secondary treatment patterns, overall survival was comparable across race. RP following AS was associated with the longest overall survival.Conclusion. Racial disparity in overall survival was not observed in this military health care beneficiary cohort with an equal access to health care.
机译:介绍。有关过度治疗前列腺癌(CaP)的担忧导致人们越来越关注主动监测(AS)。这项研究检查了AS的CaP幸存者,并通过种族/民族比较了二级治疗模式和总体生存率。研究人群包括1989年至2008年间在前列腺疾病研究中心(CPDR)多中心国家数据库中按AS自我分类为黑人或白人的CaP患者,其次为AS。二级治疗包括根治性前列腺切除术(RP),体外放射治疗或近距离放射治疗(EBRT-Br)和激素疗法(HT)。通过种族/民族比较二级治疗模式和总生存率。在886名合格患者中,有21%是黑人。尽管风险特征和二级治疗模式存在种族差异,但不同种族的总生存率相当。 AS后的RP与最长的总​​生存期有关。在这个享有平等医疗服务的军事医疗受益人群中,未观察到总体生存的种族差异。

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