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Psoriasis in childhood: effective strategies to improve treatment adherence

机译:儿童牛皮癣:改善治疗依从性的有效策略

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Abstract: Psoriasis is a relatively common chronic inflammatory skin disease in children for which there is no cure. Most children have mild disease that can be managed with topical therapy as opposed to phototherapy or systemic therapy. Despite the mild presentation of psoriasis in most children, the disease can have a significant impact on quality of life due to the need for ongoing treatment, the frequently visible nature of the cutaneous manifestations, and the social stigma that is associated with psoriasis. Adherence to treatment, in particular topical therapy, is often poor in adults and compromises response to therapy and medical provider management strategies. Multiple factors that may contribute to nonadherence in adults with psoriasis have been identified, including lack of education on the disease and expectations for management, issues related to ease of use and acceptability of topical medications, and anxiety regarding possible medication side effects. There is currently no published data on adherence in the pediatric psoriasis population; however, poor adherence is often suspected when patients fail to respond to appropriate therapy. General strategies used to assess adherence in other pediatric disease populations can be applied to children with psoriasis, and interventions that reflect experience in other chronic dermatologic disorders such as atopic dermatitis may also be helpful for medical providers caring for children with psoriasis.
机译:摘要:银屑病是一种相对较常见的慢性炎症性皮肤病,无法治愈。大多数儿童患有轻度疾病,可通过局部治疗而不是光疗或全身治疗来控制。尽管在大多数儿童中银屑病呈轻度表现,但由于需要持续治疗,皮肤表现的频发性和与银屑病有关的社会污名,该病仍可能对生活质量产生重大影响。成人对治疗尤其是局部治疗的依从性通常较差,并且损害了对治疗和医疗提供者管理策略的反应。已经确定了可能导致成人牛皮癣不依从的多种因素,包括缺乏对该疾病的教育和对治疗的期望,与局部药物的易用性和可接受性有关的问题以及对可能的药物副作用的焦虑。目前尚无有关小儿牛皮癣人群依从性的数据。但是,当患者对适当的治疗方法无效时,通常会怀疑依从性差。用于评估其他儿科疾病人群依从性的一般策略可以应用于银屑病儿童,反映其他慢性皮肤病(如特应性皮炎)经验的干预措施也可能对护理银屑病儿童的医疗提供者有所帮助。

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