Diversity-Oriented Synthesis and Chemical Genetics of Peptidomimetics to Address Lead Discovery of Anti-Infective Agents

Lenci Elena; Stefanini Irene; Guarna Antonio; Menchi Gloria; Cavalieri Duccio; Trabocchi Andrea

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Diversity-Oriented Synthesis and Chemical Genetics of Peptidomimetics to Address Lead Discovery of Anti-Infective Agents

机译：拟肽的多样性导向的合成和化学遗传学，以解决抗感染剂的潜在发现

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Modern advances in Chemical Biology include the improvement of screening methods, the introduction of bioinformatic methods to unravel biological pathways, and the generation of highquality chemical libraries. [...]

机译：化学生物学的现代进展包括筛选方法的改进，引入生物信息学方法以揭示生物学途径以及生成高质量化学文库的过程。 [...]

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《Proceedings》 |2017年第6期|共页
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Lenci Elena; Stefanini Irene; Guarna Antonio; Menchi Gloria; Cavalieri Duccio; Trabocchi Andrea;
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中图分类文化、科学、教育、体育;
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1. Diversity-Oriented Synthesis and Chemical Genetics of Peptidomimetics to Address Lead Discovery of Anti-Infective Agents [J] . Lenci Elena, Stefanini Irene, Guarna Antonio, Proceedings . 2017,第6期

机译：拟肽的多样性导向的合成和化学遗传学，以解决抗感染剂的潜在发现
2. Chemical genetics approach to drug discovery by diversity-oriented synthesis (DOS) of peptidomimetics [J] . Trabocchi A., Cavalieri D., Guarna A. Pure and Applied Chemistry . 2011,第3期

机译：化学遗传学方法通过拟肽的面向多样性的合成（DOS）发现药物
3. Diversity-oriented synthesis of pyrazoles derivatives from flavones and isoflavones leads to the discovery of promising reversal agents of fluconazole resistance in Candida albicans [J] . Cui Chang-Yi, Liu Jun, Zheng Hong-Bo, Bioorganic and Medicinal Chemistry Letters . 2018,第9期

机译：来自黄酮和异黄酮的吡唑衍生物的分量为吡唑衍生物的合成导致发现念珠菌抗甘蓝醛抗性的有前途的逆转剂
4. Novel synthesis of small peptidomimetic macrocyclic libraries with conformational diversity:discovery of IGF-1R inhibitors [C] . Nir Qvit, Hadas Reuveni, Sharon Gazal International Peptide Symposium;European Peptide Symposium . 2005

机译：具有构象多样性的小肽致癌致癌物质文库的新合成：IGF-1R抑制剂的发现
5. Discovery of small molecule probes for chemical genetics using biased and unbiased diversity-oriented organic synthesis. [D] . Wong, Jason Christopher. 2004

机译：使用有偏和无偏的面向多样性的有机合成发现用于化学遗传学的小分子探针。
6. Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach [O] . Jinbao Xiang, Zhuoqi Zhang, Yan Mu, -1

机译：面向多样性的合成与融合筛选方法相结合发现新型三环噻嗪类衍生物作为抗药性的抗癌药物
7. Diversity-Oriented Synthesis of Diol-Based Peptidomimetics as Potential HIV Protease Inhibitors and Antitumor Agents [O] . Paresh M. Vadhadiya, Marc-Alexandre Jean, Chahrazed Bouzriba, 2018

机译：基于二醇的肽模拟物的分量为潜在的HIV蛋白酶抑制剂和抗肿瘤剂

Diversity-Oriented Synthesis and Chemical Genetics of Peptidomimetics to Address Lead Discovery of Anti-Infective Agents

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