Edema Disease of Swine: A Review of the Pathogenesis.

摘要

Edema disease (ED) is an often-fatal enterotoxemia produced by specific pathogenic strains of Escherichia coli in weaner and feeder pigs, with major importance in porcine production, management and health. ED is also used as a naturally occurring disease model for the severe systemic pathologies caused by Shiga toxin-producing Escherichia coli (STEC) in humans. Recently, porcine strains of STEC are also receiving attention from a food safety and public health perspective. In this review, we briefly discuss and outline the current knowledge regarding the pathogenesis of ED in pigs, with particular reference to the gross and microscopic features of the disease.