Sleep apnoea in patients with nocturnal hypertension – a multicenter study in the Czech Republic.

摘要

Sleep apnoea (SA) is common in patients with hypertension.Nowadays, limited data on the prevalence of SA in nocturnalhypertension (NH) exist. Therefore, we studied the occurrence ofSA in Czech patients and its association with 24-h ambulatoryblood pressure monitoring (ABPM), breathing disturbances insleep, anthropometric data, Mallampati score and Epworthsleepiness scale (ESS) using the Apnea Link device. UndiagnosedSA was found in 72.9 % patients (29.3 % mild, 26.6 %moderate, 17.0 % severe) of 188 patients with NH measuredby ABPM. The median of the apnoea-hypopnoea index (AHI)was 12.0 (25th-75th percentile 5.0-23.8). Moderate/severe SA(AHI≥15) was associated with BMI, waist circumference, meannight saturation (SpO2), t90, oxygen desaturation index (ODI),ESS (daytime BP only) (p≤0.032), but not ABPM parameters andMallampati score (p0.09). A likelihood of moderate/severe SAwas enhanced by ODI14.5 events/h (odds ratio=57.49,95 % CI=22.79-145.01), t906.5 % (8.07, 4.09-15.92), meannight SpO229.05 kg/m2 (6.22,3.10-12.49), circum waist105.5 cm (3.73, 1.57-8.83), but notby any ABPM parameter. In conclusion, a high incidence of SA(72.9 %) was observed in Czech patients with NH. SA severitywas associated with body characteristics and oxygenationparameters, but not with ABMP parameters and Mallampatiscore.