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首页> 外文期刊>St. Petersburg Polytechnic University Journal: Physics and Mathematics >The new method for studying neuronal activity: Optogenetics
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The new method for studying neuronal activity: Optogenetics

机译:研究神经元活动的新方法:光遗传学

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The article is devoted to problems of realization and application of optogenetic methods used to identify reasons of various diseases, to monitor the biochemical processes of cell activity and to study various organisms. The problems of delivery, embedding and monitoring the expression of opsin genes into the cell genome of interest have been considered. In the article, the parameters and properties of various opsins and also the main ways of achievement of precise optical control over cell using opsins were presented. The rules for choosing the parameters of a light beam and the features of its putting were pointed out. The characteristic properties of the different measurement technique and recording the experimental quantities were analyzed and given.
机译:本文致力于解决光遗传学方法的实现和应用问题,这些方法用于识别各种疾病的原因,监测细胞活性的生化过程以及研究各种生物。已经考虑了将视蛋白基因的表达递送,嵌入和监测到目的细胞基因组中的问题。本文介绍了各种视蛋白的参数和性质,以及使用视蛋白对细胞进行精确光学控制的主要方法。指出了光束参数的选择规则和其放置的特点。分析并给出了不同测量技术和记录实验量的特性。

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