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Incidence of Spontaneous Resorption of Lumbar Disc Herniation: A Meta-Analysis

机译:腰椎间盘突出症自然吸收的发生率:一项荟萃分析

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BACKGROUND: Lumbar disc herniation (LDH), a common disease, is often treated conservatively, frequently resulting in spontaneous resorption of the herniated disc. The incidence of this phenomenon, however, remains unknown.OBJECTIVE: To analyze the incidence of spontaneous resorption after conservative treatment of LDH using computed tomography and magnetic resonance imaging.STUDY DESIGN: Meta-analysis and systematic review of cohort studies.SETTING: The work was performed at The Suzhou Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine.METHODS: We initiated a search for the period from January 1990 to December 2015 using PubMed, Embase, and the Cochrane Library. Two independent reviewers examined the relevant reports. The references from these reports were also searched for additional trials using the criteria established in the PRISMA statement.RESULTS: Our results represent the pooled results from 11 cohort studies. The overall incidence of spontaneous resorption after LDH was 66.66% (95% CI 51% – 69%). The incidence in the United Kingdom was 82.94% (95% CI 63.77% – 102.11%). The incidence in Japan was 62.58% (95% CI 55.71% – 69.46%).LIMITATIONS: Our study was limited because there were few sources from which to extract data, either in abstracts or published studies. There were no randomized, controlled trials that met our criteria.CONCLUSIONS: The phenomenon of LDH reabsorption is well recognized. Because its overall incidence is now 66.66% according to our results, conservative treatment may become the first choice of treatment for LDH. More large-scale, double-blinded, randomized, controlled trials are necessary to study the phenomenon of spontaneous resorption of LDH.Key words: Lumbar, disc herniation, spontaneous resorption, conservative treatment, incidence, country, meta-analysis, systematic review, observational studies, study designs
机译:背景:腰椎间盘突出症(LDH)是一种常见疾病,通常经过保守治疗,经常导致椎间盘突出症的自然吸收。目的:通过计算机断层扫描和磁共振成像分析保守治疗LDH后自发吸收的发生率研究设计:荟萃分析和队列研究的系统评价。方法:我们使用PubMed,Embase和Cochrane图书馆对1990年1月至2015年12月这一时期进行了搜索。两名独立审稿人审阅了相关报告。还使用PRISMA声明中确立的标准对这些报告的参考文献进行了检索,以寻找其他试验。结果:我们的结果代表了11个队列研究的汇总结果。 LDH后自发吸收的总发生率为66.66%(95%CI 51%– 69%)。英国的发病率为82.94%(95%的CI为63.77%– 102.11%)。日本的发病率为62.58%(95%CI 55.71%– 69.46%)。局限性:我们的研究是有限的,因为从摘要或已发表的研究中提取数据的来源很少。没有符合我们标准的随机对照试验。结论:LDH重吸收现象已得到广泛认可。根据我们的结果,由于其总体发生率现在为66.66%,因此保守治疗可能成为LDH治疗的首选。研究LDH的自发吸收现象需要更多的大规模,双盲,随机对照试验。关键词:腰椎,椎间盘突出症,自发吸收,保守治疗,发生率,国家,荟萃分析,系统评价,观察研究,研究设计

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