Laser-Assisted Orthodontic Tooth Movement in Saudi Population: A Prospective Clinical Intervention of Low-Level Laser Therapy in the 1st Week of Pain Perception in Four Treatment Modalities

摘要

Background. )is first-in-human study in Saudi orthodontic patients has evaluated the role of low-level laser therapy (LLLT) inpain perception (PP). )e outcome of single application of LLLT with 4 different treatment modalities (TM) on PP are evaluatedfollowing orthodontic bracket bonding on maxilla. Materials and Methods. A prospective clinical intervention with implementationof parallel technique in each group, 32 orthodontic patients with ectopic canine requiring fixed orthodontic appliancewere enrolled and randomly allocated to the 4 groups: LLLT + self-ligating (SL) bracket, LLLT + conventional (Conv.) bracket,non-LLLT + SL bracket, and non-LLLT + Conv. bracket. Orthodontic bracket bonding from 1st molar to 1st molar andsuperelastic 0.012 inch NiTi were applied for the maxilla. For each patient, maxillary 1st molar to molar received a singleapplication of LLLT using a 940 nm Ga-Al-As laser device on 5 different points labially/buccally and palatally. Main outcomemeasure was the degree of PP score during the 1st week of orthodontic tooth movement (OTM) after 4 hours, 24 hours, 3 days,and 7 days of both LLLT and non-LLLT treatment applications. A questionnaire with an 11-point numeric rating scale (NRS) wasused for PP. Results. Mean ± SD of PP in the LLLT + SL group was 3.33 ± 1.4, 3.58 ± 1.06, 2.31 ± 0.67, and 1.89 ± 0.54 in 4 hours, 24hours, 3 days, and 7 days, respectively. Compared to all 4 TM groups, LLLTgroups showed better PP. More statistically significantdifferences were found in LLLT groups. No harms were encountered. Limitations. )e intervention provider and the patient werenot blinded to the intervention. Conclusion. )e LLLT + SL group revealed significantly promising benefits on PP during OTM.