Impacts of residual renal function (RRF) on clinical and laboratory features of chronic hemodialysis patients

摘要

Objective: To study the effect of residual renal function (RRF) on clinical and laboratory features of chronic haemodialysis patients. Background: Residual renal function (RRF) in patients with end-stage renal disease (ESRD) is defined as the ability of native kidneys to eliminate water and uremic toxins. Studying the impacts on haemodialysis patients will guide nephrologist for better preservation of (RRF) and so improve outcome of their patients. Patients and Methods: The clinical and laboratory data of 73 regular haemodialysis patients(more than 3 months) of dialysis unit at our Department of Internal Medicine and during a 6 month period from October 2016 to March 2017 were reviewed in a retrospective manner the patients classified according to presence of (RRF) and not to two groups. Results: this study reveal that hypertension is the main cause of renal failure in both groups and show significant correlation between(RRF)(positive for group having residual function) and ultrafiltration rate, serum creatinine, serum potassium, haemoglobin level, serum iron, transferrin saturation, intact parathyroid hormone and CRP and no correlation between (RRF) and blood pressure, heart rate, body mass index, serum urea, serum sodium, calcium, phosphorus, uric acid, serum ferritin and serum albumin. Conclusion: residual renal function has clinical and laboratory effects on our patients of residual and provide them better survival than patients of non residual. Our study about (RRF) on dialysis patients confirms most of the findings of previous studies that clarify the importance of (RRF) on patients' survival and the importance of its preservation.