Etiología del autismo: el continuo idiopático-sindrómico como tentativa explicativa

摘要

Although already none doubt that the autism spectrum disorders (ASD) constitute a myriad of clinical syndromes, linked to neurodevelopment, there are still many questions that needbe answered. Thus, researchers focus their efforts in genetic disorders that are in the origin ofsecondary autism, for to know more aboutprimary autism (or idiopathic), whose concrete causeis ignored. Delving into this, we review here recent findings in the research of such disorders,convinced that there is a primary-secondary autism continuum that rigorous studies in moleculargenetics must show. However, there is much pathology with autistic behaviors whose etiologyremains still unknown. In this line, aside from books, were selected indexed articles in MEDLINE,published from 2008 to 2015, related to advances in genetic research and diagnosis from autisticspectrum disorder. Like key words were used "autism", and the paired-words combinations of "autism and etiology", "autism and neurodevelopment" and "autism and genetics".