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Endemic dengue: surveillance strategy challenges

机译:地方性登革热:监测策略的挑战

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Interaction between clinical infection, vector, and population serotype immunity defines dengue epidemic risk. An endemic-sporadic epidemiological situation is an acceptable control target in metropolitan regions deficient in urban upgrading, sanitation, and health agents' access to residences, besides low residual power of biological insecticides and social mobilization problems. Surveillance requires continued action by government and society (particularly when incidence decreases) and adequate proposals. To establish a sensitive and specific surveillance system for endemic periods, the authors propose the sentinel clinical component as part of emergency care (detecting serious tip-of-the-iceberg cases) and reference services for acute febrile diseases, defining clinical forms and providing diagnostic confirmation. Although complex, sample serotype surveys should be conducted in strategic areas, evaluating: immunity and susceptibility of age groups to circulating serotypes; estimation of sub-clinical cases; and Surveillance and Control System reach.
机译:临床感染,媒介和人群血清型免疫力之间的相互作用决定了登革热的流行风险。在缺乏城市升级,卫生设施和卫生机构无法获得住所的大都市地区,除了生物杀虫剂的残留力低和社会动员问题之外,地方性零星流行病学状况是可以接受的控制目标。监视需要政府和社会继续采取行动(尤其是在发生率下降时),并提出适当的建议。为了建立针对流行期的敏感而特定的监视系统,作者建议将前哨临床组件作为紧急护理(检测严重的冰山一角病例)的一部分,并为急性发热性疾病提供参考服务,定义临床形式并提供诊断确认。尽管很复杂,但应在战略领域进行血清型抽样调查,评估:年龄组对循环血清型的免疫力和敏感性;估计亚临床病例;和监控系统达到。

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