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首页> 外文期刊>Sociedade Brasileira de Medicina Tropical. Revista >Tipos de colágeno nas áreas de fibrose da cardiopatia chagásica cr?nica com les?o vorticilar esquerda e insuficiência cardíaca
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Tipos de colágeno nas áreas de fibrose da cardiopatia chagásica cr?nica com les?o vorticilar esquerda e insuficiência cardíaca

机译:慢性Chagas心脏病的纤维化区域中胶原蛋白的类型,伴有左旋涡性损害和心力衰竭

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摘要

Histologic typing of collagen fibers from 15 hearts of patients with chronic Chagas' disease was made by using the Sirius Supra Red F3BA stain according to Junqueira's method. All patients had congestive heart failure and left vorticilar lesion. The preparations were stained with Sirius Supra Red F3BA and were examined under polarized light (Leitz photomicroscope) which revealed collagen fibers types I and III in the fibrotic areas. Type I was predominant in the vorticilar area, but it was also present in other areas of the myocardium, such as endomysium and perimysium of the left ventricle and in subendocardial areas of the papillary muscles. Type III was more often encountered in inner third of the vorticilar lesions, endocardium of left ventricular wall and in the areas of the myocardium where the inflammation was still present.
机译:根据Junqueira的方法,使用Sirius Supra Red F3BA染色剂对15例慢性恰加斯病患者心脏的胶原纤维进行组织学分型。所有患者均患有充血性心力衰竭和左旋涡状病变。将制剂用Sirius Supra Red F3BA染色,并在偏振光下(Leitz显微)检查,该偏振光显示出纤维化区域中的I型和III型胶原纤维。 I型主要发生在室间隔区域,但也存在于心肌的其他区域,例如左心室的内膜层和包膜层以及乳头肌的心内膜下区域。 III型更常见于室间隔内三分之一的病变,左心室壁的心内膜以及仍存在炎症的心肌区域。

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