Numerical and experimental investigation on the breast cancer tumour parameters by inverse heat transfer method using genetic algorithm and image processing

摘要

This study presents numerical and experimental investigation on breast cancer tumour parameters by inverse heat transfer method using genetic algorithm (GA) and image processing (IP) to determine the depth and rate of heat generation of a breast cancer tumour. To simulate the problem, using the energy equation in acylinder including a heater, the surface temperature distribution was obtained. Then, the temperature surface of the cylinder was analysed by the GA in MATLAB software to determine the depth and rate of heat generation of heater. The validity of the numerical method was evaluated using the IP from a laboratory sample. A thermal heater was placed inside a cylinder and was covered by a tissue similar to the human body tissue. According to the obtained results, it was determined that the results of the laboratory sample and the numerical method were in agreement with each other. Finally, these steps were applied on the thermal image of a patient’s cancer breast to determine the depth and rate of heat generation of the breast tumour. It is shown that the average computational error between numerical and experimental results in this method to determine the depth of the tumour isabout 8–10% and to determine the rate of tumour heat generation is about 0.01–1%.