Anti-gbm Rapidly Progressive Glomerulonephritis (Syndroma Goodpasture): A Case Report

摘要

Goodpasture syndrome is a severe illness caused by the formation of antibodies to the glomerular basement membrane and alveolus with consequential damage to renal and pulmonary function. With current therapy, long-term survival is more than 50%. Before, the mortality was higher than 90%. In our patient, the disease began as dysuria, continued as anaemic syndrome, and ended with the development of end-stage renal failure. Immunosuppressive therapy with pulse doses of methylprednisolone and cyclophosphamide has put the disease into remission, but the permanent impairment of renal function remained. Early diagnosis of Goodpasture syndrome helps preserve renal function and improves patients’ survival. In patients who achieve remission, a kidney transplant can be considered. Currently, our patient is awaiting transplantation.