Actinomycetoma due to Actinomadura madurae: A therapeutic challenge. Case report

摘要

Mycetoma is a chronic granulomatous infection that develops after traumatic inoculation of the skin with either true fungi (eumycetoma) or aerobic actinomycetes (actinomycetoma). Can be found in geographic areas in close proximity to the Tropic of Cancer also known as ‘‘mycetoma belt’’, the predominant climate of this region is subtropical and dry tropical. Actinomycetomas caused by Actinomadura spp. occur in drier areas with low relative humidity. We report a case in a 45 years-old female, with a 9-years history of a progressive inflammatory tumor, sinuses tracts and granules on her left sole. She was treated with antibiotics and amputation without improvement. Actinomycetoma due to A. madurae was confirmed and successfully treated with a combination therapy that included streptomycin plus trimethoprim/sulfamethoxazol.