Staphylococcus sp. Involvement in Community Acquired Urinary Tract Infections

摘要

The aim of this study was to investigate the contribution of Staphylococcus species to the etiology of community acquired urinary tract infections (UTI) in Romanian population, and to investigate their antibiotic resistance profiles. 6,250 urine samples were collected between August - October 2014 by Synevo Laboratory (Bucharest), out of which the overall isolation rate of Staphylococcus spp. was 2.68% (n = 50). S. saprophyticus was the most frequent isolated species, being susceptible to methicillin but 28% exhibited an efflux-mediated macrolides resistance phenotype. S. aureus was the second most commonly isolated, exhibiting combined MRSA (methicillin-resistant Staphylococcus aureus) (encoded by SSCmec type Ill and IVa gene cassettes) and inducible resistance to macrolide, lincosamide, streptogramin B (MLSBi) phenotypes. The S. haemolyticus and S. lugdunensis strains were isolated with a lower frequency (2 strains each) and one S. lugdunensis strain harboured SSCmec type III cassette. Our results highlight differences in the etiology of community acquired UTI from those reported in other geographical areas, proving the necessity of knowing the local etiology and resistance markers in order to design appropriate empirical therapy regimens and to monitor the antimicrobial resistance emergence and spread in community.