SYNTHESIS AND SPECTRAL CHARACTERIZATION OF SCHIFF BASE TRANSITION METAL COMPLEXES, DNA CLEAVAGE AND ANTIBACTERIAL ACTIVITY STUDIES

摘要

A new string of transitional metal complexes of Cu(II), Zn(II) and Ni(II) have been synthesized from the Schiff base ligand derived from 2,4-dihydroxybenzaldehyde and p-aminobenzoic acid. Structural studies were obtained by their elemental analysis, magnetic susceptibility, molar conductance, IR, UV-Visible, 1 H-NMR and ESR spectral studies. The data shows that the complexes have a composition of ML type. The UV-Visible, magnetic susceptibility and ESR spectral data of the complexes proposed square planar geometry about the metal ion except for zinc complex. The redox behavior of the complexes was studied by cyclic voltammetry. An antimicrobial screening test shows good results in the presence of metal ion than in the ligand.