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首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Alogenic platelet lysate in necrosis of the torn piece
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Alogenic platelet lysate in necrosis of the torn piece

机译:同种异体血小板溶解产物在坏死片坏死中的作用

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The use of allogenic platelet lysate opens another therapeutic possibility in orthopedics. Its use is presented in a 40 year-old patient with previous history of bronchial asthma and treated with steroids who, as a result a fall, suffered an extensive avulsive wound in her right foot of approximately 11 cm with skin laceration and necrosis of the torn piece, with vertex distal and proximal base that only took skin, with another torn piece of similar bodering and a diameter of approximatety 6 cm. A toilette and necrectomy of the cyanotic edge was made, mainly in the vertexes. Confrontation stitches were taken and an extreme fragility of the skin was observed when carrying this procedure. Treatment with antibiotics was started and after 48 hours necrosis of two third of the skin of the torn piece was observed which was not removed for ten days. After removal local therapy with alogenic platelet lysate was applied on alternate days. Improving of granulation was observed, but not in the surrounding skin lesion. Then, a perilessional infiltration with allogenic platelet lysate was made which improved the lesion appearance and its healing in a period of only 7 days.
机译:同种异体血小板裂解物的使用为骨科打开了另一种治疗可能性。一名40岁有支气管哮喘病史并曾接受过类固醇治疗的患者介绍了这种药物的使用,该类固醇因摔倒而在右脚遭受了约11 cm的广泛撕脱性伤口,皮肤撕裂伤和坏死一块,其远端和近端基部仅吸收皮肤,另一块类似的边缘撕裂,直径约6厘米。进行了紫te边缘的淡化和肾切除术,主要在顶点。进行对针缝合后,进行此程序时观察到皮肤极度脆弱。开始用抗生素治疗,并且在48小时后,观察到撕裂片的三分之二的皮肤坏死,其在十天内没有去除。取出后,隔天使用含基因的血小板裂解物进行局部治疗。观察到肉芽的改善,但在周围皮肤病变中没有。然后,用异基因血小板裂解物进行了无周浸润,仅在7天的时间内就改善了病灶的外观及其愈合。

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