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Dosimetric verification of radiotherapy treatment planning systems in Serbia: national audit

机译:塞尔维亚放射治疗计划系统的剂量学验证:国家审核

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Background Independent external audits play an important role in quality assurance programme in radiation oncology. The audit supported by the IAEA in Serbia was designed to review the whole chain of activities in 3D conformal radiotherapy (3D-CRT) workflow, from patient data acquisition to treatment planning and dose delivery. The audit was based on the IAEA recommendations and focused on dosimetry part of the treatment planning and delivery processes. Methods The audit was conducted in three radiotherapy departments of Serbia. An anthropomorphic phantom was scanned with a computed tomography unit (CT) and treatment plans for eight different test cases involving various beam configurations suggested by the IAEA were prepared on local treatment planning systems (TPSs). The phantom was irradiated following the treatment plans for these test cases and doses in specific points were measured with an ionization chamber. The differences between the measured and calculated doses were reported. Results The measurements were conducted for different photon beam energies and TPS calculation algorithms. The deviation between the measured and calculated values for all test cases made with advanced algorithms were within the agreement criteria, while the larger deviations were observed for simpler algorithms. The number of measurements with results outside the agreement criteria increased with the increase of the beam energy and decreased with TPS calculation algorithm sophistication. Also, a few errors in the basic dosimetry data in TPS were detected and corrected. Conclusions The audit helped the users to better understand the operational features and limitations of their TPSs and resulted in increased confidence in dose calculation accuracy using TPSs. The audit results indicated the shortcomings of simpler algorithms for the test cases performed and, therefore the transition to more advanced algorithms is highly desirable.
机译:背景技术独立的外部审核在放射肿瘤学的质量保证计划中起着重要作用。由塞尔维亚国际原子能机构支持的审计旨在审查3D保形放射治疗(3D-CRT)工作流程的整个活动链,从患者数据获取到治疗计划和剂量提供。审计是根据原子能机构的建议进行的,重点是治疗计划和交付过程中的剂量测定部分。方法审核是在塞尔维亚的三个放射治疗部门进行的。用计算机断层摄影设备(CT)扫描拟人化体模,并在局部治疗计划系统(TPS)上为国际原子能机构建议的涉及不同束配置的八个不同测试案例制定治疗计划。按照这些测试用例的治疗计划照射体模,并使用电离室测量特定点的剂量。报告了测量剂量与计算剂量之间的差异。结果针对不同的光子束能量和TPS计算算法进行了测量。使用高级算法制作的所有测试用例的测量值与计算值之间的偏差均在一致性标准之内,而对于较简单的算法,则观察到较大的偏差。结果数量超出协议标准的测量次数随着束能量的增加而增加,而随着TPS计算算法的成熟而减少。同样,检测并纠正了TPS中基本剂量学数据中的一些错误。结论审核帮助用户更好地了解其TPS的操作特征和局限性,并提高了使用TPS剂量计算准确性的信心。审计结果表明,对于所执行的测试案例而言,较简单的算法存在缺陷,因此非常需要过渡到更高级的算法。

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