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A novel implementation of mARC treatment for non-dedicated planning systems using converted IMRT plans

机译:使用转换后的IMRT计划对非专用计划系统进行mARC处理的新方法

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Background The modulated arc (mARC) technique has recently been introduced by Siemens as an analogue to VMAT treatment. However, up to now only one certified treatment planning system supports mARC planning. We therefore present a conversion algorithm capable of converting IMRT plans created by any treatment planning system into mARC plans, with the hope of expanding the availability of mARC to a larger range of clinical users and researchers. As additional advantages, our implementation offers improved functionality for planning hybrid arcs and provides an equivalent step-and-shoot plan for each mARC plan, which can be used as a back-up concept in institutions where only one linac is equipped with mARC. Methods We present a feasibility study to outline a practical implementation of mARC plan conversion using Philips Pinnacle and Prowess Panther. We present examples for three different kinds of prostate and head-and-neck plans, for 6 MV and flattening-filter-free (FFF) 7 MV photon energies, which are dosimetrically verified. Results It is generally more difficult to create good quality IMRT plans in Pinnacle using a large number of beams and few segments. We present different ways of optimization as examples. By careful choosing the beam and segment arrangement and inversion objectives, we achieve plan qualities similar to our usual IMRT plans. The conversion of the plans to mARC format yields functional plans, which can be irradiated without incidences. Absolute dosimetric verification of both the step-and-shoot and mARC plans by point dose measurements showed deviations below 5% local dose, mARC plans deviated from step-and-shoot plans by no more than 1%. The agreement between GafChromic film measurements of planar dose before and after mARC conversion is excellent. The comparison of the 3D dose distribution measured by PTW Octavius 729 2D-Array with the step-and-shoot plans and with the TPS is well above the pass criteria of 90% of the points falling within 5% local dose and 3 mm distance to agreement. For all plans, the treatment time was noticeably reduced by conversion to mARC. Conclusions We present the feasibility test for converting IMRT step-and-shoot plans from the RTP-output of any treatment planning system (Philips Pinnacle and Prowess Panther, in our case) into mARC plans. The feasibility and dosimetric equivalence is demonstrated for the examples of a prostate and a head-and-neck patient.
机译:背景技术西门子最近引入了调弧(mARC)技术,作为VMAT处理的模拟。但是,到目前为止,只有一个经过认证的治疗计划系统支持mARC计划。因此,我们提出了一种转换算法,该算法能够将任何治疗计划系统创建的IMRT计划转换为mARC计划,希望将mARC的可用性扩展到更大范围的临床用户和研究人员。作为额外的优势,我们的实施提供了改进的功能,可用于规划混合电弧,并为每个mARC计划提供了等效的分步计划,可在只有一个直线加速器装有mARC的机构中用作备份概念。方法我们提出了一项可行性研究,概述了使用Philips Pinnacle和Prowess Panther进行mARC计划转换的实际实施。我们提供了三种不同类型的前列腺计划和头颈计划的例子,分别针对6 MV和无展平滤波器(FFF)7 MV光子能量进行了剂量学验证。结果通常,在Pinnacle中使用大量的光束和很少的分段来创建高质量的IMRT计划通常比较困难。我们以不同的优化方式为例。通过仔细选择光束和分段布置以及反演目标,我们可以获得与常规IMRT计划相似的计划质量。将计划转换为mARC格式会生成功能计划,可以对其进行照射而不会发生任何事故。通过点剂量测量对分步拍摄和mARC计划进行绝对剂量学验证,显示偏差低于5%局部剂量,mARC计划与分步拍摄计划的偏差不超过1%。 GafChromic膜测量mARC转换前后的平面剂量之间的一致性非常好。通过PTW Octavius 729 2D阵列,分步拍摄计划和TPS测量的3D剂量分布的比较远高于90%的通过标准,这些点落入5%局部剂量和3 mm距离内协议。对于所有计划,通过转换为mARC可以显着减少治疗时间。结论我们提出了将任何治疗计划系统(在我们的情况下为Philips Pinnacle和Prowess Panther)的RTP输出中的IMRT分步拍摄计划转换为mARC计划的可行性测试。对于前列腺和头颈患者的实例证明了可行性和剂量等效。

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