A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies

NA Doria-Rose; I Georgiev; RP Staupe; S O’Dell; G Chuang; J Gorman; JS McLellan; M Pancera; M Bonsignori; BF Haynes; DR Burton; WC Koff; PD Kwong; JR Mascola

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A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies

机译：HIV-1 gp120 V1 / V2区域中的一小段是对PG9样抗体的中和抗性的主要决定因素

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《Retrovirology》 |2012年第s2期|共页
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NA Doria-Rose; I Georgiev; RP Staupe; S O’Dell; G Chuang; J Gorman; JS McLellan; M Pancera; M Bonsignori; BF Haynes; DR Burton; WC Koff; PD Kwong; JR Mascola;
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中图分类细胞生物化学;
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1. N-Glycans in the gp120 V1/V2 domain of the HIV-1 strain NL4-3 are indispensable for viral infectivity and resistance against antibody neutralization. [J] . Wolk T, Schreiber M Medical Microbiology and Immunology . 2006,第3期

机译：HIV-1菌株NL4-3的gp120 V1 / V2结构域中的N-聚糖对于病毒感染性和对抗体中和的抗性而言必不可少。
2. Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies. [J] . Mondor I, Moulard M, Ugolini S, Virology . 1998,第2期

机译：HIV gp120，CD4和CXCR4之间的相互作用：依赖CD4表达水平，gp120病毒起源，gp120 COOH-和NH2-末端以及V1 / V2和V3环的保守性以及对中和抗体的敏感性。
3. Impact of amino acid substitutions in the V2 and C2 regions of human immunodeficiency virus type 1 CRF01_AE envelope glycoprotein gp120 on viral neutralization susceptibility to broadly neutralizing antibodies specific for the CD4 binding site [J] . Piraporn Utachee, Panasda Isarangkura-na-ayuthaya, Kenzo Tokunaga, Retrovirology . 2014,第S1期

机译：人类免疫缺陷病毒1型CRF01_AE包膜糖蛋白gp120的V2和C2区域中的氨基酸取代对病毒中和敏感性的影响，对中和CD4结合位点特异性抗体的敏感性
4. 3D models for conformational states of the V3 and V1/V2 loops in gp120/CD4/antibody complex [C] . Stan Galaktionov, Gregory V.Nikiforovich, Garland R.Marshall the International Peptide Symposium . 2001

机译：V3和V1 / V2循环的构象状态的3D模型，GP120 / CD4 /抗体复合物
5. Two Sides to the Same Antibody: Assessing the Role of Neutralizing and Non-neutralizing Antibodies in Mother-to-child Transmission of HIV-1 [D] . Ghulam-Smith, Melissa 2021

机译：两侧到同一抗体：评估中和和非中和抗体在HIV-1的母儿传播中的作用
6. A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies [O] . NA Doria-Rose, I Georgiev, RP Staupe, 2012

机译：HIV-1 gp120 V1 / V2区域中的一小段是对PG9样抗体的中和抗性的主要决定因素
7. A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies [O] . NA Doria-Rose, I Georgiev, RP Staupe, 2013

机译：HIV-1 gp120 V1 / V2区域中的一小段是对PG9样抗体的中和抗性的主要决定因素

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies

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