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Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study

机译:加纳剖宫产术后粘连发生率和相关的术后并发症:一项前瞻性队列研究

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The global increase in Cesarean section rate is associated with short- and long-term complications, including adhesions with potential serious maternal and fetal consequences. This study investigated the prevalence of adhesions and association between adhesions and postoperative complications in a tertiary referral hospital in Accra, Ghana. In this prospective cohort study, 335 women scheduled for cesarean section at Korle-Bu Teaching Hospital in Accra, Ghana were included from June to December 2015. Presence or absence of adhesions was recorded and the severity of the adhesions was scored using a classification system. Associations between presence and severity of adhesions, postoperative complications, and maternal and infant outcomes at discharge and 6 weeks postpartum were assessed using multivariate logistic and linear regression analysis. Of the participating women, 128 (38%) had adhesions and 207 (62%) did not. Prevalence of adhesions increased with history of caesarean section; 2.8% with no CS but may have had an abdominal surgery, 51% with one previous CS, 62% with >1 CS). Adhesions significantly increased operation time (mean 39.2 (±15.1) minutes, absolute adjusted difference with presence of adhesions 9.6?min, 95%CI 6.4-12.8), infant delivery time (mean 5.4 (±4.8) minutes, adjusted difference 2.4?min, 95%CI 1.3-3.4), and blood loss for women with severe adhesions (mean blood loss 418.8?ml (±140.6), adjusted difference 57.6?ml (95%CI 12.1-103.0). No differences for other outcomes were observed. With cesarean section rates rising globally, intra-abdominal adhesions occur more frequently. Risks of adhesions and associated complications should be considered in counseling patients for cesarean section.
机译:剖宫产率的全球增加与短期和长期并发症有关,包括可能对母婴造成严重后果的粘连。这项研究调查了加纳阿克拉一家三级转诊医院的粘连发生率以及粘连与术后并发症之间的关联。在这项前瞻性队列研究中,纳入了2015年6月至2015年12月在加纳阿克拉Korle-Bu教学医院安排剖腹产的335名妇女。记录是否存在粘连,并使用分类系统对粘连的严重程度进行评分。使用多因素logistic和线性回归分析评估粘连的存在与严重程度,术后并发症以及出院时和产后6周的母婴结局之间的关联。在参与研究的女性中,有128位(38%)有粘连,而有207位(62%)没有。剖宫产史导致粘连发生率增加; 2.8%(没有CS,但可能进行了腹部手术),51%(曾经接受过一次CS),62%(> 1 CS))。粘连显着增加了手术时间(平均39.2(±15.1)分钟,存在粘连的绝对调整差9.6?min,95%CI 6.4-12.8),婴儿分娩时间(平均5.4(±4.8)分钟,调整差2.4?min ,95%CI 1.3-3.4)和严重粘连的女性失血(平均失血418.8?ml(±140.6),调整后的差异为57.6?ml(95%CI 12.1-103.0),其他结局无差异。随着剖宫产率的整体上升,腹腔内粘连发生的频率更高,在为患者进行剖宫产的咨询中应考虑粘连的风险和相关并发症。

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