...
首页> 外文期刊>Research Journal of Medical Sciences >Bacteriologic Profile and Antibiotics Susceptibility Pattern of Suspected Septicaemic Patients in Uyo, Nigeria
【24h】

Bacteriologic Profile and Antibiotics Susceptibility Pattern of Suspected Septicaemic Patients in Uyo, Nigeria

机译:尼日利亚乌约疑似败血症患者的细菌学特征和抗生素敏感性模式

获取原文
   

获取外文期刊封面封底 >>

       

摘要

Septicaemia is a common potentially life-threatening condition with significantly high morbidity and mortality. Due to the serious threat it poses to lives of patients and the fact that results of blood cultures take a while to be ready, effective empirical therapy would require that clinicians should be armed with the knowledge of current bacteriologic profile of septicaemia and their susceptibility patterns. This study is aimed at determining the bacterial profile of septicaemia and their susceptibility pattern in University of Uyo Teaching, South-South region of Nigeria. A total of 689 blood samples were aseptically collected from patients of various ages with suspected septicaemia admitted at University of Uyo Teaching Hospital (UUTH) from January 2011 to December 2012. The samples were inoculated into blood culture bottles containing brain heart infusion broth and thyoglycolate broth and incubated at 37°C, aerobically and anaerobically respectively. Subcultures were made, isolates were identified and antibiotics susceptibility set up using standard methods. Data was analysed using SPSS Version 16. The study showed that 161 (23.4%) were culture positive. The commonest bacterial isolates were Staphylococcus aureus (55.3%), Escherichia coli (18.0%), Klebsiella pneumoniae (11.2%) and Coagulase Negative Staphylococci (CONS) (4.3%). Ampicillin and amoxicillin/clavulanic acid were the most resistant antibiotics while imipenem and vancomycin were the most sensitive. Regular bacteriologic profile and antibiotics susceptibility surveillance studies is advocated for effective management of septicaemia.
机译:败血病是一种常见的潜在威胁生命的疾病,其发病率和死亡率都很高。由于严重威胁患者生命,血液培养的结果需要一段时间才能准备就绪,因此有效的经验疗法将要求临床医生应掌握当前败血症的细菌学特征及其易感性模式。这项研究的目的是确定尼日利亚南南地区Uyo教学大学的败血病细菌谱及其敏感性模式。从2011年1月至2012年12月在Uyo大学医院(UUTH)入院的不同年龄的疑似败血病患者中,共采集了689份血液样本。将这些样本接种到装有脑心输液肉汤和巯基乙酸胆汁的血培养瓶中。并分别在37°C,需氧和厌氧条件下孵育。进行亚培养,鉴定出分离物,并使用标准方法建立抗生素敏感性。使用SPSS版本16分析数据。研究表明161(23.4%)为培养阳性。最常见的细菌分离株是金黄色葡萄球菌(55.3%),大肠杆菌(18.0%),肺炎克雷伯菌(11.2%)和凝固酶阴性葡萄球菌(CONS)(4.3%)。氨苄西林和阿莫西林/克拉维酸是最耐药的抗生素,亚胺培南和万古霉素最敏感。提倡定期进行细菌学分析和抗生素敏感性监测研究,以有效管理败血病。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号