Serological Survey of Human Cystic Echinococcosis with ELISA Method and CHF Ag, in Moghan Plain, Ardabil Province, Iran

摘要

Cystic Echinococcosis (CE) is a zoonosis, caused by the metacestode form of Echinococcus granulosus. The diagnosis of CE is difficult using the clinical features of the disease and serological methods aimed at determining the specific antibody response. CE is medically and economically one of the important parasitic zoonoses in Iran. So far no survey was conducted to determine the rate of human hydatidosis in Ardabil Province, so using ELISA tests the prevalence of this disease was detected in Moghan area in this Province. Hospital records that the disease is frequent in Moghan area of Ardabil province. The present study designed to determine the seropositive rate and to analyse risk factors of the disease in the people living in the region. In this survey 1998 serum samples were randomaly collected from the normal population. The sera was tested using Enzyme Linked Immunosorbent- assay protocol. The serology results All the sera were examined using ELISA test and CFA Ag and Ag B. The serology results were anlysed by Logistic regression using spss 11.5. of 1998 serum samples 184 sera (9.2%) were positive. Women were more than men (10% vs 7.9%). The age group of 20-39 and 40-59 showed the highest and the 0-19 showed the lowest rate of infection.The rate of prevalence in this province shows somehow a resemblance with the other cities in Iran. Considering the lifestyle in this province a complementary study is suggested in all related cities.