Serological and Sonographical Survey of Hydatid Disease in Moghan Plain of Iran

摘要

Cystic echinococcosis is one of the most geographically widespread Helminth Zoonosis. A study was undertaken to determine spread of Human Cystic Echinococcosis among people in Moghan Plain and to evaluate the effectiveness of health education in increasing community knowledge regarding the disease. Firstly Households were interviewed using a Questionnaire to evaluate their knowledge of Hydatid disease (Cystic Echinococcosis) and the human population was registered and screened for CE by abdominal ultrasound scan as well as a number of serologic tests (ELISA) with HCF-Ag for raw screening and using specific antigens ex. Ag-B and Ag-5 for exact diagnosis. Prevalence of human CE was 9.6% (92 of 1003 sera); 0.3% (8) of the cases were new ultrasound detected asymptomatic cases (mean age = 81 years). Beginning serology results all the sera were examined using ELISA test and HCF-Ag, prevalence of human CE was 11.2% (111), afterwards the serology results all the sera were examined using Specific Antigens Such as Ag-B and Ag-5 for CE prevalence was 9.2% (84 of 1003 sera) this results determined some of the Cysts don?t excretion antigen only diagnosed with ultrasound scan. Results were analyzed by Logistic regression using SPSS 13.5. Of 1003 serum samples 84 sera 9.2% were Positive. Women were more than men (20 vs. 11.2%) for CE. The Age group of 1-19 showed the lowest rate and the 20-39 and 40-59 showed the highest rate of infection. Mass screening by US with confirmatory serologic testing is an effective approach to case detection at the everywhere of world.