Evaluation of the Antinociceptive (Anti Pain) Activity of Prosopis Africana Using Formalin Test on Rats

摘要

This research was conducted to evaluate the potency of Prosopis africana leaf extract in the treatment of pain in rats. Thework investigated the antinociceptive (anti pain) activity of the leaf extract of this plant. The experimental rats were groupedinto three; Group A negative control, the rats in this group were given 0.2ml of normal saline, Group B contained rats thatwere given 0.2ml of aspirin, this served as positive control and the last Group C were given 0.2ml of the leaf extract. At theend the rats in group A experienced the highest pain, having mean value of 2.925. But in the rats in groups B and C, therewas no significant difference (P < 0.05), having the mean values of 1.600 and 1.575 respectively. At the end of this research,it was observed that the leaf extract of Prosopis africana plant relieved pains in the rats studied.