Biological Assays and Chemical Composition of Volatile Oils of Bupleurum fruticosum L. (Apiaceae)

摘要

The composition of supercritical CO 2 extracts and essential oils obtained by hydrodistillation of Bupleurum fruticosum L., growing spontaneously in Italy and Portugal, and its antifungal activity is reported. The collected extracts were analyzed by GC-FID and GC-MS methods. The minimal inhibitory concentration (MIC) and the minimal lethal concentration (MLC) were used to evaluate the antifungal activity of the oils against Candida albicans , C. tropicalis , C. krusei , C. guillermondii , C. parapsilosis , Cryptococcus neoformans , Trichophyton rubrum , T. mentagrophytes , Microsporum canis , M. gypseum , Epidermophyton floccosum , Aspergillus niger , A. fumigatus and A. flavus .