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Assessing compliance of cardiologists with the national cholesterol education program (NCEP) III guidelines in an ambulatory care setting

机译:在门诊医疗机构中评估心脏病专家是否符合国家胆固醇教育计划(NCEP)III准则

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Introduction The NCEP III -ATP guidelines provide clear clinical directives for lipid management especially statins therapy in appropriate patient groups. Compliance of primary care physicians with these guidelines especially in ambulatory care settings has been shown to be poor. The compliance of cardiologist to these guidelines is less documented. Methods A retrospective chart review of 386 patients managed in a large urban cardiology practice was undertaken. Patients with documented contraindications to use of statins were excluded from the study. Only patients with two or more years of follow-up in the practice were included. Demographic variables and medical history including CAD or its equivalent and its major risk factors were identified. The proportion of patients on statins and adequacy of statins therapy were recorded. The lipid profiles of all patients were also analyzed. Results Fifteen patients with documented contraindications to statins therapy including persistent/severe LFT abnormalities, allergies, and gastrointestinal intolerance were excluded. A total of 371 patients were included in the analysis. The mean age for patients in the study was 65 years (range: 42–84). 236 (64%) were males while 141 (36%) were females. 161 (43%) patients were on statins while 210 (57%) weren't. 88 (62%) of females were on stain compared to 116 (49%) of males (p = 0.001). 68% of patients below the age of 50 yrs were not on statins compared with 55% of those greater than 50 yrs (p = 0.01). 38% of patients on statins therapy had sub-optimal lipid profile despite greater than two years of therapy. No statistically significant differences in race and use of satins were noted. Conclusion This study demonstrates a higher than expected prevalence of sub-optimal management of dyslipidemia among patients with established coronary heart disease without contraindications to statins managed by cardiologists. Cardiology and primary care practices require similar comprehensive routine lipid management program that is assiduously maintained and evaluated at both in-patient and out patient settings to ensure most patients receive optimal therapy with statins and other lipid lowering agents.
机译:简介NCEP III -ATP指南为适当的患者群体中的脂质管理(尤其是他汀类药物治疗)提供了明确的临床指导。初级保健医师对这些指导原则的依从性很差,尤其是在门诊护理环境中。心脏病专家对这些指导原则的依从性较少。方法对回顾性图表回顾性分析386例在大型城市心脏病实践中管理的患者。有使用他汀类药物禁忌证的患者被排除在研究之外。仅包括在实践中进行了两年或更长时间随访的患者。确定了人口统计学变量和病史,包括CAD或同等水平及其主要危险因素。记录接受他汀类药物的患者比例和他汀类药物治疗的充分性。还分析了所有患者的脂质分布。结果排除了15例他汀类药物禁忌证患者,包括持续性/严重LFT异常,过敏和胃肠道不耐受。分析中总共包括371名患者。研究中患者的平均年龄为65岁(范围:42–84)。男性为236名(64%),而女性为141名(36%)。 161名(43%)患者使用他汀类药物,而210名(57%)未使用他汀类药物。 88位女性(62%)被染色,男性116位(49%)(p = 0.001)。年龄在50岁以下的患者中有68%的人未使用他汀类药物,而年龄在50岁以上的患者中有55%的患者未使用他汀类药物(p = 0.01)。他汀类药物治疗的患者尽管接受了两年以上的治疗,但仍有38%的患者血脂不足。注意到在种族和使用沙汀方面没有统计学上的显着差异。结论本研究表明,在没有心脏病专家管理的他汀类药物禁忌症的情况下,已确诊的冠心病患者血脂异常亚最佳治疗的患病率高于预期。心脏病学和初级保健实践需要类似的综合性常规血脂管理程序,该程序必须在患者内外进行严格维护和评估,以确保大多数患者接受他汀类药物和其他降脂药的最佳治疗。

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