Abstract：Objective To observer the clinical effect of DNA immunoadsorption therapy in treatment of systemic lupus erythematosus (SLE) and to summarize the nursing management. Methods A total of 21 SLE patients undergoing 48 times of DNA immunoadsorption therapy were included in this study. Nursing measures were provided mainly focusing on psychological states, diet, vascular access, side reaction and complication of patients. Results The symptom such as anorexia and fatigue were improved in all 21 SLE patients after DNA immunoadsorption therapy. The serum level of antidsDNA autoantibody was decreased 2 weeks after treatment compared with that before treatment (P＜0.01). The main side reaction was thrombocytopenia, which was reported in two cases during observation period. Conclusion DNA immunoadsorption therapy is an important way of treating SLE, and proper nursing measures should be applied to ensure the therapeutic effect.
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