：Objective To investigate the effect of scraping therapy in treatment of knee osteoarthritis(KOA). Methods 〓Totally 80 patients with KOA were assigned to the moxibustion group and the scraping therapy group, with 40 cases in each group. Patients in both two groups received functional exercise and moxibustion therapy, and those in the scraping therapy group were given scraping therapy. The serum indexes of interleukin-1(IL-1), interleukin-6, tumor necrosis factor-alpha(TNF-α)and superoxide dismutase(SOD)were detected before and after treatment. The clinical syndrome integral and Visual Analogue Scale(VAS)on pain of patients were assessed. The clinical efficacy of the treatment was evaluated and compared between two groups. Results 〓Patients in the scraping therapy group received a better outcomes of serum IL-1、IL-6、TNF-α and SOD compared with those in the moxibustion group at two months after treatment(P0.01). The scores of clinical syndrome integral and VAS on pain were decreased in two groups at two months after treatment, and were lower in the scraping therapy group than those in the moxibustion group(P0.05). The overall effective rate in the scraping therapy group was higher than that in the control group(87.50% vs. 67.50%, P0.05). Conclusion 〓The scraping therapy is potentially effective to ameliorate the clinical symptom and pain degree of patients with KOA.
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