SUN-147 TARGETING CD103+ DENDRITIC CELLS USING FLT3 INHIBITORS FOR TREATMENT OF KIDNEY DISEASE; RELEVANCE TO HUMAN KIDNEY DISEASE.

摘要

Innate lymphoid cells (ILCs) are a recently recognized group of immune cells with critical roles in tissue homeostasis and inflammation. Regulatory innate lymphoid cells ([LCregs) are a newly identified subset of ILCs, which play a suppressive role in the innate immune response, fa- voring the resolution of intestinal inflammation. However, the expression and role of ILCregs in kidney has not been reported.