Health-related quality of life in chronic kidney desease: Predictive relevance of mood and somatic symptoms

摘要

Objective To compare the predictive capacity of self-reported somatic symptoms and mood (depression and anxiety) on health-related quality of life (HRQoL) in patients with chronic renal disease. Method Data were obtained from 52 patients undergoing haemodialysis. Measures included (a) the SF-36 health survey, (b) the somatic symptoms scale revised (ESS-R) and (c) the hospital anxiety and depression scale (HADS). Multiple regression was the main method of statistical analysis. Results Patients exhibited HRQoL levels below normative values, with anxiety and depression prevalence at 36.5% and 27%, respectively. Mood was the strongest predictor of physical ( β = ?.624) and mental ( β = ?.709) HRQoL. Somatic symptoms were also associated with physical HRQoL, but their predictive value was weaker ( β = ?.270). Conclusions These results indicate that mood is a superior predictor of the physical and mental components of HRQoL in patients compared with the number and severity of physical symptoms. The data underline the importance of assessing negative emotional states (depression and anxiety) in kidney patients as a basis for intervention, which may facilitate reduction of the impact of chronic renal disease on HRQoL.