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Biological Activities and Valuable Compounds from Five Medicinal Plants

机译:五种药用植物的生物活性和有价值的化合物

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Currently, there are more than 85,000 plant species that have been documented for medical use globally. This implies, plant derived natural products hold great promise for discovery and development of new pharmaceuticals in diverse human ailments. Among these divers medicinal species Aframomum corrorima, Commiphora myrrha, Nigella sativa, Ocimum lamiifolium and Olea europaea are one of very well known valuable plants in serving the local people as spice, flavor, fumigants, and sources of traditional and modern medicines. In modern science their medicinal activities have been corroborated by phytochemical and biological research investigations. As the biological studies revealed they have antibacterial, antioxidant, antifungal, antimicrobial and anti-inflammatory properties even though further investigation required on in vivo and animal model to ascertain those in vitro activities are really valuable in life. The phytochemical investigations have also shown that these plants are holder of diversified useful compound classes like terpene, steroid, flavonoid, glycoside, fatty acid and alkaloids. However, their pharmacology and pharmacokinetics activities have to be further investigated in order to make sure their metabolic effect upon their usage because some compounds have ability to be metabolized during in vivo analysis, and to see whether these compounds have synergic or additive effects. Therefore, the purpose of this review paper is to present the compiled and unified scientific studies which have been done on the above well known medicinal plants about their description, medicinal uses, volatile and extracted active compounds, and chemical structures of isolated compounds in justification with scientific researches.
机译:目前,全球已记录有超过85,000种植物用于医疗用途。这意味着,植物衍生的天然产物有望在多种人类疾病中发现和开发新药物。在这些潜水员中,药用农杆菌,没药Commonphora myrrha,Nigella sativa,Ocimum lamiifolium和油橄榄(Olea europaea)是为当地人提供香料,风味,熏蒸剂以及传统和现代药物来源的非常有价值的植物之一。在现代科学中,通过植物化学和生物学研究证实了它们的药用活性。生物学研究表明,它们具有抗菌,抗氧化剂,抗真菌,抗微生物和抗炎特性,尽管需要对体内和动物模型进行进一步研究以确定这些体外活性对生命确实有价值。植物化学研究还表明,这些植物拥有多种有用的化合物类别,如萜烯,类固醇,类黄酮,糖苷,脂肪酸和生物碱。但是,由于某些化合物具有在体内分析过程中代谢的能力,并确保这些化合物具有协同作用或加成作用,因此必须进一步研究其药理作用和药代动力学活性,以确保其在使用后的代谢作用。因此,本综述的目的是介绍已对上述知名药用植物进行的汇编和统一科学研究,这些研究涉及它们的描述,药用用途,挥发性和提取的活性化合物以及分离的化合物的化学结构,以证明其合理性。科学研究。

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