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A Case of Essential Thrombocythemia Complicated by Acute Myocardial Infarction

机译:原发性血小板增多症并发急性心肌梗死一例

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摘要

Essential thrombocythemia, a subcategory of chronic myeloproliferative disorder, is characterized by absolute thrombocytosis due to excessive clonal proliferation of platelets, hyperaggregability of platelets and increased incidence of thrombosis and hemorrhage. Essential thrombocythemia may cause frequent vascular thrombosis, but it can be a rare cause of acute ischemic heart diseases such as acute myocardial infarction without atherosclerosis, unstable angina and angina pectoris. We report a case of essential thrombocythemia complicated by acute myocardial infarction. A patient with a previous history of vascular thrombotic complications (such as transient ischemic attack and deep vein thrombosis) was managed with 2.8 million units of intravenous urokinase, antiplatelet agent, ACEI, antianginal medications and hydroxyurea. There were clinically remarkable improvements and no further episodes of thrombotic ischemic vascular complications, including acute myocardial infarction.
机译:原发性血小板增多症是慢性骨髓增生性疾病的一个子类别,其特征在于绝对血小板增多症是由于血小板的过度克隆增殖,血小板过度凝集和血栓形成和出血的发生率增加所致。原发性血小板增多症可能会导致频繁的血管血栓形成,但它可能是急性缺血性心脏病的罕见原因,例如无动脉粥样硬化的急性心肌梗塞,不稳定的心绞痛和心绞痛。我们报告一例原发性血小板增多症并发急性心肌梗塞。先前有血管血栓并发症(例如短暂性脑缺血发作和深静脉血栓形成)病史的患者接受了280万单位的静脉尿激酶,抗血小板药,ACEI,抗心绞痛药物和羟基脲治疗。临床上有显着改善,没有进一步发作血栓性缺血性血管并发症,包括急性心肌梗塞。

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