PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway

Meilin Shi; Menghan Cao; Jun Song; Qinghua Liu; Hailong Li; Fei Meng; Zhenqiang Pan; Jin Bai; Junnian Zheng

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PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway

机译：PinX1通过抑制NF-κB/ MMP-9信号通路抑制人乳腺癌的侵袭和转移

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Background PinX1 (PIN2/TRF1-interacting telomerase inhibitor 1) was suggested to be correlated with tumor progression. This study was designed to evaluate the role of PinX1 in human breast cancer.

机译：背景PinX1（与PIN2 / TRF1相互作用的端粒酶抑制剂1）被认为与肿瘤进展相关。这项研究旨在评估PinX1在人类乳腺癌中的作用。

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《Molecular Cancer 》 |2015年第1期| 共页
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Meilin Shi; Menghan Cao; Jun Song; Qinghua Liu; Hailong Li; Fei Meng; Zhenqiang Pan; Jin Bai; Junnian Zheng;
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1. Curcumol Suppresses Breast Cancer Cell Metastasis by Inhibiting MMP-9 Via JNK1/2 and Akt-Dependent NF-κB Signaling Pathways [J] . Ling Ning, Hui Ma, Zhuyun Jiang, Integrative cancer therapies. . 2016 ,第2期

机译：姜黄素通过抑制JNK1 / 2和Akt依赖性NF-κB信号通路的MMP-9抑制乳腺癌细胞转移。
2. Formononetin Inhibits Migration and Invasion of MDA-MB-231 and 4T1 Breast Cancer Cells by Suppressing MMP-2 and MMP-9 Through PI3K/AKT Signaling Pathways. [J] . R Zhou, L Xu, M Ye, Hormone and Metabolic Research . 2014 ,第11期

机译：Formononetin通过PI3K / AKT信号通路抑制MMP-2和MMP-9，从而抑制MDA-MB-231和4T1乳腺癌细胞的迁移和侵袭。
3. Frondoside A has an anti-invasive effect by inhibiting TPA-induced MMP-9 activation via NF-κB and AP-1 signaling in human breast cancer cells [J] . Sun Young Park, Young Hun Kim, YoungHee Kim, International journal of oncology . 2012 ,第3期

机译：Frondoside A通过抑制人乳腺癌细胞中TPA诱导的经由NF-κB和AP-1信号传导的MMP-9活化而具有抗侵袭作用
4. Dieckol from Ecklonia cavaRegulates Invasion of Human Fibrosarcoma Cells andModulates MMP-2 and MMP-9 Expression via NF-κB Pathway [C] . Chen Zhang, Yong Li, Zhong-Ji Qian, International Marine Biotechnology Conference . 2010

机译：Ecklonia cava的Dieckol调节人纤维肉瘤细胞的侵袭并通过NF-κB途径调节MMP-2和MMP-9表达
5. Activation of matrix metalloproteinase -9 (MMP-9) by heregulin in human breast cancer cells involves multiple signaling pathways. [D] . Yao, Jun. 2000

机译：调蛋白在人乳腺癌细胞中对基质金属蛋白酶-9（MMP-9）的激活涉及多个信号通路。
6. PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway [O] . Meilin Shi, Menghan Cao, Jun Song, 2015

机译：PinX1通过抑制NF-κB/ MMP-9信号通路抑制人乳腺癌的侵袭和转移
7. PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway [O] . 2015

机译：PinX1通过抑制NF-κB/ MMP-9信号通路抑制人乳腺癌的侵袭和转移
8. Targeting SIAH E3 Ligase Downstream of the HER2/Neu/RAS Signaling Pathway to Block Tumorigenesis and Metastasis of Highly Invasive Human Breast Cancer. [R] . Tang, A. H. 2012

机译：针对HER2 / Neu / Ras信号通路下游的sIaH E3连接酶阻断高侵袭性人乳腺癌的肿瘤发生和转移。

PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway

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