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首页> 外文期刊>Memórias do Instituto Oswaldo Cruz >Complete plasmid sequence carrying type IV-like and type VII secretion systems from an atypical mycobacteria strain
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Complete plasmid sequence carrying type IV-like and type VII secretion systems from an atypical mycobacteria strain

机译:携带非典型分枝杆菌菌株的IV型和VII型分泌系统的完整质粒序列

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The genus Mycobacterium is highly diverse and ubiquitous in nature, comprehending fast- and slow-growing species with distinct impact in public health. The plasmid-mediated horizontal gene transfer represents one of the major events in bacteria evolution. Here, we report the complete sequence of a 160,489 bp circular plasmid (pCBMA213_2) from an atypical and fast-growing environmental mycobacteria. This is a unique plasmid, in comparison with the characterised mycobacteria plasmids, harboring a type IV-like and ESX-P2 type VII secretion systems. pCBMA213_2 can be further explored for evolutionary and conjugation studies as well as a tool to manipulate DNA within this bacteria genus.
机译:分枝杆菌属在自然界中是高度多样化和普遍存在的,包括快速增长和缓慢增长的物种,对公共卫生产生显着影响。质粒介导的水平基因转移代表细菌进化中的主要事件之一。在这里,我们报告了来自非典型和快速增长的环境分枝杆菌的160,489 bp环状质粒(pCBMA213_2)的完整序列。与表征的分枝杆菌质粒相比,这是独特的质粒,具有IV型和ESX-P2 VII型分泌系统。 pCBMA213_2可以进一步用于进化和缀合研究,以及在该细菌属中操纵DNA的工具。

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