Transcription activation in bacteria: ancient and modern

Stephen J. W. Busby

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Transcription activation in bacteria: ancient and modern

机译：细菌中的转录激活：古代和现代

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Regulatory interactions at the lac promoter.Activation of the transcription of genes is central to many processes of adaptation and differentiation in bacteria. Here, I review the molecular mechanisms by which transcription factors can activate the initiation of specific transcripts at bacterial promoters. The story is presented in the context of Marjory Stephenson’s pioneering work on enzymatic adaptation in bacteria, and sets the different mechanisms in the greater context of how transcription regulatory mechanisms evolved.

机译：lac启动子之间的调节相互作用。基因转录的激活对于细菌适应和分化的许多过程至关重要。在这里，我回顾了转录因子可以激活细菌启动子上特定转录物起始的分子机制。这个故事是在Marjory Stephenson在细菌中进行酶适应的开创性背景下呈现的，并在转录调控机制如何进化的更大背景下设定了不同的机制。

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《Microbiology》 |2019年第4期|共10页
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Stephen J. W. Busby;
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中图分类微生物学;
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activatorsBacterial transcriptionDNA-dependent RNA polymerasepromoters;

机译：激活剂细菌转录DNA依赖性RNA聚合酶启动子;

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Transcription activation in bacteria: ancient and modern

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