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Nanomaterials – Proposals of occupational exposure limits in the world and hygiene standards in Poland

机译:纳米材料–关于世界职业接触限值和波兰卫生标准的提案

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Currently, there are no legally binding workplace exposure limits for substances in the form of nanoobjects. There are different approaches to risk assessment and determination of occupational exposure limits. The purpose of this article is to compare exposure levels in the work environment proposed by international organizations and world experts, as well as the assumptions and methods used for their estimation. This paper presents the proposals of the National Institute for Public Health and the Environment in the Netherlands (RIVM), the New Energy and Industrial Technology Development Organization in Japan (NEDO) and the National Institute for Occupational Safety and Health in the USA (NIOSH). The authors also discuss the reports on the levels for carbon nanotubes (Baytubes? and Nanocyl) proposed by Pauluhn and Luizi, the derived no-effect levels (DNEL) complying with the REACH Regulation, proposed by experts under the 7th Framework Programme of the European Commission, coordinated by Professor Vicki Stone (ENRHES), and alternative estimation levels for poorly soluble particles by Pauluhn. The issue was also raised whether the method of determining maximum admissible concentrations in the work environment, currently used in Poland, is adequate for nanoobjects. Moreover, the introduction of nanoreference values, as proposed by RIVM, the definition of a new fraction for particles of 1-100 nm, taking into account the surface area and activity of the particles, and an adequate estimation of uncertainty factors seem to be worth considering. Other important, if not key issues are the appropriate measurement (numerical concentration, surface concentration, particle size distribution), as well as the methodology and equipment accessibility to all employers responsible for a reliable risk assessment of exposure to nanoparticles in the work environment. Med Pr 2013;64(6):829–845
机译:当前,对于纳米物体形式的物质,没有任何具有法律约束力的工作场所暴露极限。风险评估和职业接触限值的确定方法不同。本文的目的是比较国际组织和世界专家提出的工作环境中的暴露水平,以及用于估算的假设和方法。本文介绍了荷兰国家公共卫生与环境研究所(RIVM),日本新能源与工业技术开发组织(NEDO)和美国国家职业安全与卫生研究所(NIOSH)的建议。 。作者还讨论了Pauluhn和Luizi提出的有关碳纳米管(Baytubes?和Nanocyl)水平的报告,以及符合REACH法规的衍生无效应水平(DNEL),该水平由专家根据欧洲第七框架计划提出。由Vicki Stone教授(ENRHES)协调的委员会,Pauluhn对难溶性颗粒的替代估算水平。还提出了一个问题,即波兰目前使用的确定工作环境中最大容许浓度的方法是否适用于纳米物体。此外,如RIVM所建议的那样,引入纳米参考值,定义1-100 nm粒子的新分数,考虑到粒子的表面积和活性以及对不确定性因素进行充分估计似乎是值得的考虑。其他重要的问题(如果不是关键问题)是适当的测量(数字浓度,表面浓度,粒度分布),以及负责对工作环境中的纳米颗粒暴露进行可靠风险评估的所有雇主的方法和设备可及性。 Med Pr 2013; 64(6):829–845

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