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70% Alcohol Versus Dry Cord Care in the Umbilical Cord Care: A Case–Control Study in Italy

机译:70%的酒精对脐带护理中的干脐带护理:意大利的病例对照研究

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Recently the use of antibacterial agents to clean and dry the stump of the newborns’ umbilical cord (UC) after birth has been abandoned by many neonatal units in favor of dry cord care. Aim of this study was to compare the occurrence of adverse events (AEs) and time to cord separation among newborns treated with dry cord care versus 70% alcohol in an Italian Academic Hospital (AH). From December 2014 to March 2015, 239 infants were born at the AH. The number of eligible infants was 200 and they were equally assigned to either case group (dry cord care) or control group (70% alcohol, standard procedure). Standard cord care consisted in 1 application of 70% alcohol at birth followed by other 2 times a day, while experimental dry cord care procedure was executed by the only application of a sterile gauze around the base of the UC at the 1st day of life and after the cord has been exposed to air off the diaper edge. The time to UC separation and any AEs such as local and systemic infections, hemorrhage, and granuloma formation were reported by mothers. We found a significant difference in the mean cord separation time between the 2 groups (dry cord care: 10.1 days [standard deviation, SD?=?4.0] vs 70% alcohol: 12.0 days [SD?=?4.2]; P Dry cord care is an easy, straight-forward, and safe method of handling the UC in healthy newborn infants born in a high-income hospital setting.
机译:最近,许多新生儿单位已放弃使用抗菌剂清洁和干燥新生儿脐带(UC)的残端,而倾向于干脐带护理。这项研究的目的是比较在意大利学术医院(AH)中接受干脐带护理与70%酒精治疗的新生儿的不良事件(AE)发生和脐带分离时间。从2014年12月到2015年3月,在AH出生了239名婴儿。符合条件的婴儿数为200,并将他们平均分为病例组(干脐带护理)或对照组(70%酒精,标准程序)。标准的脐带护理包括在出生时1次使用70%的酒精,然后每天其他2次,而实验性的干脐带护理程序是在生命的第一天和之后仅在UC底部周围应用无菌纱布进行的,脐带从尿布边缘暴露在空气中后。母亲报告了UC分离的时间和任何AE,例如局部和全身感染,出血和肉芽肿形成的时间。我们发现两组之间的平均脐带分离时间有显着差异(干脐带护理:10.1天[标准偏差,SD?=?4.0]与70%酒精:12.0天[SD?=?4.2]; P干线在高收入医院环境中出生的健康新生儿中,护理是一种简便,直接且安全的方法,可以处理UC。

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