Renal function, serum sodium level, and outcomes in hospitalized systolic heart failure patients: An analysis of the COAST study

摘要

Both renal function and serum sodium level are well-known prognostic markers in heart failure (HF) patients. We investigated the prognostic value of the renal impairment (RI) stratified by the serum sodium level in systolic HF patients. The Clinical Characteristics and Outcomes in Relation with Serum Sodium Level in Asian Patients Hospitalized for Heart Failure (the COAST) Study enrolled hospitalized systolic HF patients (ejection fraction Of 1462 enrolled patients, 716 patients (49%) had RI (GFR2), and they had higher 12-month mortality than those without RI (22.8% vs. 10.9%, PP In hospitalized Asian HF-patients both RI and low sodium level are independent risk factors. Patients with both RI and low serum sodium level are at the highest risk and may require meticulous medical care.